产品货号：
Z33050
中文名称：
AKT1抗体
英文名称：
Anti-AKT1 Antibody (Clone#OTI4D6)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AKT1 Antibody (Clone#OTI4D6) |
| 指标别名 | AKT;AKT1;PKB;PKB ALPHA;PRKBA;Protein kinase B;Proto oncogene c Akt;RAC;RAC ALPHA;RAC PK alpha |
| 克隆性 | Monoclonal |
| 检验物种 | human,monkey,mouse,rat,dog |
| 应用范围 | WB,IHC,IF,FCM |
| 基因名称 | AKT1 |
| 克隆号 | OTI4D6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Full length human recombinant protein of human AKT1(NP_005154) produced in HEK293T cell. |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | RAC-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene.The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts.AKT1 and the related AKT2 are activated by platelet-derived growth factor.The activation is rapid and specific,and it is abrogated by mutations in the pleckstrin homology domain of AKT1.It was shown that the activation occurs through phosphatidylinositol 3-kinase.In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival.Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1,which then phosphorylates and inactivates components of the apoptotic machinery.Mutations in this gene have been associated with the Proteus syndrome.Multiple alternatively spliced transcript variants have been found for this gene. |
| Uniprot ID | P31749 |
| 基因名全称 | v-akt murine thymoma viral oncogene homolog 1 |
| 蛋白名全称 | RAC-alpha serine/threonine-protein kinase |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:150 Immunofluorescence (IF) 1:100 Flow cytometry (FCM) 1:100 |
相关搜索：AKT1抗体，AKT1单抗，Anti-AKT1 Antibody (Clone#OTI4D6)